Coming in March, Women At Work will offer over a dozen workshops and classes to help clients find a job, improve job skills, train for new job, and manage resources while looking for a job. In the month of March, look for the following classes:â€¢ QuickBooks2â€¢ Applying Quickbooksâ€¢ First Impressions Are Forever (Learn How to Dress to Win!)â€¢ The Employer Forum (One of our Most Popular Events)â€¢ Publisherâ€¢ Networking Mixerâ€¢ Job Searching on the Internetâ€¢ Living on a Shoestring BudgetLook on line for specifics and registration by logging on the website at www.womenatwork.org call (626) 796-6870 and keep checking back! We are always looking to add more. Sliding scale for qualifying participants is available. Classes fill quickly, so make your reservations today!For more training opportunities, visit the website or visit the center to 3871 E Colorado Blvd in Pasadena, Monday through Thursday between the hours of 9:30am and 4:30pm. The office is open Wednesdays until 7pm. Women At Work is working for every one! Non-Profits News Upcoming Classes at Women At Work Assist Job Seekers From STAFF REPORTS Published on Wednesday, February 27, 2013 | 12:04 pm Name (required) Mail (required) (not be published) Website Your email address will not be published. Required fields are marked * Home of the Week: Unique Pasadena Home Located on Madeline Drive, Pasadena Pasadena’s ‘626 Day’ Aims to Celebrate City, Boost Local Economy HerbeautyAmazing Sparks Of On-Screen Chemistry From The 90-sHerbeautyHerbeautyHerbeauty5 Things To Avoid If You Want To Have Whiter TeethHerbeautyHerbeautyHerbeauty9 Hollywood Divas Who Fell In Love With WomenHerbeautyHerbeautyHerbeautyInstall These Measures To Keep Your Household Safe From Covid19HerbeautyHerbeautyHerbeauty11 Yummy Spices For A Flat TummyHerbeautyHerbeautyHerbeauty10 Of The Most Notorious Female Spies In HistoryHerbeautyHerbeauty Business News First Heatwave Expected Next Week EVENTS & ENTERTAINMENT | FOOD & DRINK | THE ARTS | REAL ESTATE | HOME & GARDEN | WELLNESS | SOCIAL SCENE | GETAWAYS | PARENTS & KIDS Top of the News More Cool Stuff 15 recommended0 commentsShareShareTweetSharePin it Make a comment Subscribe Community News faithfernandez More » ShareTweetShare on Google+Pin on PinterestSend with WhatsApp,Pulse PollVirtual Schools PasadenaHomes Solve Community/Gov/Pub SafetyCitizen Service CenterPASADENA EVENTS & ACTIVITIES CALENDARClick here for Movie Showtimes Get our daily Pasadena newspaper in your email box. Free.Get all the latest Pasadena news, more than 10 fresh stories daily, 7 days a week at 7 a.m. Community News Pasadena Will Allow Vaccinated People to Go Without Masks in Most Settings Starting on Tuesday
A strategy that has been shown to reduce age-related health problems in several animal studies may also combat a major cause of age-associated infertility and birth defects.Investigators from Harvard-affiliated Massachusetts General Hospital (MGH) have shown that restricting the caloric intake of adult female mice prevents a spectrum of abnormalities, such as extra or missing copies of chromosomes that arise more frequently in egg cells of aging female mammals. Their report appears in this week’s online Early Edition of the Proceedings of the National Academy of Sciences USA.“We found that we could completely prevent, in a mouse model, essentially every aspect of the declining egg quality typical of older females,” says Jonathan Tilly, director of the Vincent Center for Reproductive Biology in the MGH Vincent Department of Obstetrics and Gynecology, who led the study. “We also identified a gene that can be manipulated to reproduce the effects of dietary caloric restriction and improve egg quality in aging animals fed a normal diet, which gives us clues that we may be able to alter this highly regulated process with compounds now being developed to mimic the effects of caloric restriction.”Many studies have found that animals whose food intake is restricted but still sufficient to avoid malnutrition live longer and show fewer signs of aging than do animals given access to as much food as they want. The long-term effects of a caloric restriction (CR) diet in humans are being investigated in ongoing studies, but some health improvements, including reductions in cholesterol levels and other cardiovascular risk factors, have already been reported. An earlier study by Tilly’s group found that female mice maintained on a CR diet during most of their adulthood maintained their fertility into very advanced ages, even after being allowed to resume free feeding.A key step in the development of reproductive cells — sperm and eggs — is a process called meiosis, in which sperm and egg cell precursors with two copies of each chromosome are divided into specialized reproductive cells with a single copy of each chromosome. When mature egg and sperm cells fuse, the resulting embryo has two copies of each chromosome, one from the male and one from the female. Meiosis-associated abnormalities, such as extra or missing copies of chromosomes, are more common in the eggs of aging animals and are responsible for a greater incidence of infertility, miscarriage, and birth defects such as Down syndrome, which is caused by an extra copy of chromosome 21.Following up on their earlier finding on the impact of CR on fertility in mice, the MGH team took a closer look at metabolic factors that may underlie those results. They first followed two groups of female mice from young adulthood (3 months of age) to 1 year, an age when egg quality and fertility normally would be greatly diminished. One group was allowed to free-feed throughout adulthood, while the other was maintained on a CR diet for about seven months and returned to free-feeding for the last month of the study period. While the free-fed mice showed the expected age-related decline both in the number of egg cells released at ovulation and in how many of those eggs were mature and ready for fertilization, the eggs cells of the aged CR mice more closely resembled healthy eggs of young adult females during their prime reproductive life.Analysis of chromosomes and other meiosis-related aspects of the egg cells revealed significant abnormalities in cells from aged free-fed mice, while egg cells of the aged CR mice showed no evidence of aging-associated abnormalities. Since the age-associated decline in egg cell quality has been associated with changes in the distribution throughout the cytoplasm of mitochondria — subcellular structures that provide cellular energy — the researchers looked at the effects of diet on those cellular power plants. Again, the age-associated changes seen in the free-fed mice — aggregation of mitochondria into clumps and a drop in levels of ATP, the metabolic fuel produced by mitochondria — were not seen in egg cells from the aged CR females.While the mechanisms by which caloric restriction produces its effects are still being investigated, several of the metabolic pathways involve a regulator of DNA transcription called PGC-1α, which is known to modulate genes involved in controlling mitochondrial number and function. Tilly’s team also found that egg cells from female mice lacking a functional PGC-1α gene who were allowed to free-feed through adulthood maintained the same egg cell quality as seen in the CR mice. However, combining CR with PGC-1α inactivation did not increase the effects beyond those achieved separately, which suggests that the two approaches work in a common pathway.“While most of the work in the field of caloric restriction has been done in mice and other laboratory animals, over the past few years a number of studies have shown that several of the health benefits reported in aging mice are also seen in monkeys and perhaps in human populations that have chosen to limit their caloric intake,” says Tilly, who is a professor of obstetrics, gynecology, and reproductive biology at Harvard Medical School.“If we find a way to safely reproduce in humans the effects we see in this study — and even though this is a mouse study, we know these age-related egg cell defects are also seen in humans — we may be able both to improve a woman’s chance of getting pregnant and, for those who do need assisted reproductive technology, to improve the quality of the eggs we use to minimize if not eliminate the age-related increase in Down syndrome and other chromosomal disorders,” he adds.The study was supported by a National Institutes of Health MERIT award and by grants from the Henry and Vivian Rosenberg Philanthropic Fund, the Sea Breeze Foundation, and Vincent Memorial Research Funds.
Welcome to the Gamescom 2019 News Site!Here you will find all the Alienware and Dell happenings at Gamescom 2019, including information about product launches, event coverage and business news. #Alienware #Gamescom2019Quick Links:Gamescom Event Page Press ReleaseEvent Details: Venue Location: Koelnmesse, Cologne, North Rhine-Westphalia, GermanyAlienware & Dell Gaming Product Showcase – Hall 7, Stand B030 Date/time: Launch Event (by invitation only): Monday August 19, at 6 pm Cologne local timeWill also be streamed on Alienware.tv Coverage: Tune in to Alienware.tv Tuesday, August 20th – Saturday, August 24th for event coverage.Schedule of Events: Photos: Social: Public Days: Wednesday, August 21 – Saturday, August 24Gamescom Badge required for entry
106SHARESShareShareSharePrintMailGooglePinterestDiggRedditStumbleuponDeliciousBufferTumblr by: Gerri DetweilerIf you’re not a member of a credit union, you may wonder why anyone is. You don’t see their ATMs all over town, nor do you hear much about their state-of-the-art mobile capabilities. Yet some people sing their praises, and prefer them to banks. Both kinds of financial institutions typically offer checking accounts, savings accounts, CDs, car loans, mortgages, credit cards and other financial products. So really, what’s the difference?First, banks are in business to make money, and credit unions are nonprofit. If you do business with a bank, you are a customer. Banks exist to earn a profit for shareholders. If you instead use a credit union, you are a member (and the credit union operates for the benefit of its members); there are no shareholders or customers. And credit unions tend to use money from fees and interest rates for the benefit of members, who may also serve on their governing boards.But as financial institutions they can look very much alike from the outside. Here are some things credit unions offer that banks have a hard time matching:1. Competitive Car Loans continue reading »
THE Guyana Football Federation (GFF) yesterday began work on the country’s first football stadium – the FIFA Forward Programme.With works on the 8.5 acres land which was leased from the Eccles/Ramsburg Neighbourhood Democratic Council, Nabi and Sons was sub-contracted to work along with Greenfields and should see the first phase completed by the end of January, 2018.The key activity executed yesterday was the clearing of the field by the local contractor S. Nabi and Sons Ltd to prepare same for further works.President of the GFF, Wayne Forde, during a visit said he was happy that works have commenced, adding, “We’re happy to see movement on the ground. We will be keeping our members and the general public fully informed throughout the project.”The first phase of the project will see the construction of the artificial turf by Greenfields, a manufacturer of artificial turf. Other aspects of the facility will include dormitories, kitchen services, a gym and a pool.According to Forde, approximately 24 months is estimated for the completion of the entire facility, and he was certain that the project is “going to make a tremendous impact on the way football is operated in Guyana. Much of the encampment services that we’re involved in really requires a massive investment from the Federation”.Under the FIFA Forward Programme, National Federations are entitled to US$750 000 annually, but, in the case of Guyana, given the fact that it is the country’s first, Forde said that FIFA wanted to ensure that as much resources as possible are available, and as such, it was not possible for him to state the estimated cost of the entire project.The GFF president also noted that next, the GFF and FIFA will look to build a similar structure in Linden, and then Rupununi, after which, the other parts of Guyana will ‘fall in line’.
Riveting football action will go down at the Ministry of Education Ground tomorrow as the ExxonMobil Under-14 League heads into the semi-final round.Over the past month, the teens from secondary schools all across the coast of Guyana have been tirelessly competing weekend after weekend just to make it to this stage. Like the round-robin segment, the semis are expected to hold stunning upsets and brilliant exhibitions of young talent.Despite not being able to make it into the top four, the remaining teams in the competition will be given the opportunity to play exhibition games for the remaining slots. This method will allow for them to be ranked within the top eight.While the other teams will play for the lower spots in order to save face, the big battles will go down after the semi-finals are staged.In the female division, the formidable South Ruimveldt side will face off with East Ruimveldt Secondary. South Ruimveldt, having drawn one game and won all the others, have been very confident about their chances of reaching the final. However, the underdog East Ruimveldt team will be entering the semis with an upset on their agenda.The other semi-final will showcase a determined New Campbellville side and a determined Charlestown Secondary team. While New Campbellville have lost one of their three games, Charlestown will be entering the semis with a blemish-free record. New Campbellville will be playing to break that winning streak, but Charlestown’s public relations rep is confident that the team has what it takes to make it through.The male semis are also expected to be thrillers, with the first match up being contested by St John’s College and North Ruimveldt Multilateral. Both teams stumbled earlier in the tournament, but will seek to make the most of their shot at the final.However, the undisputable headliner of the day will come when Chase Academy and Buxton Youth Developers meet. Both teams have been dominant in the competition; as such, the excitement for this semi-final should mirror the anticipation that World Cup fans felt during the Brazil v Belgium match-up. Saturday’s action will begin at 11:00h with the girls’ exhibition match.
The Yes campaign celebrate at the count centre in Bonagee.Daniel and Majella O’Donnell were celebrating yesterday after the yes vote in the marriage equality referendum.Many felt it was the singer’s very public backing of the yes campaign which helped to swing many older voters into voting yes.Daniel on stageAlthough Daniel remained silent, Majella took to social media to express her delight at the yes vote.Although Daniel remained silent, wife Majella took to social media to express her delight at the vote. She tweeted “I think we’re a mighty little island today!!! I feel so proud to be Irish!!!”On polling day Majella had also encouraged as many people as possible to get out and cast their vote.She said “Some people think that their one little vote won’t matter. If everyone thought that way there would be no votes for anything! Use your vote today.”Majella even retweeted a joke about Daniel getting behind the yes vote.It read “Overheard in Dub-2 ladies in late 70’s “Mary which do I tick to support the Gays?It was Daniel O’Donnell changed my mind.” Daniel and his wife have returned to Ireland and plan to spend the summer months in Kincasslagh and around Ireland.They are also awaiting the arrival of their first grandchild as Majella’s daughter Siobhan revealed that she is five months pregnant.Siobhan, 27, and her fiancé Gavin Shields are understood to be expecting their first child at the end of July.Majella (54) said that the family are “absolutely delighted” with the news.Gavin and Siobhan became engaged last Christmas.DANIEL AND MAJELLA DELIGHTED AT ‘YES’ VOTE! was last modified: May 25th, 2015 by StephenShare this:Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on Reddit (Opens in new window)Click to share on Pocket (Opens in new window)Click to share on Telegram (Opens in new window)Click to share on WhatsApp (Opens in new window)Click to share on Skype (Opens in new window)Click to print (Opens in new window) Tags:daniel o’donnellMajellayes vote
Despite his recent injury, Warriors guard Stephen Curry still plans to play for USA Basketball during the 2020 Tokyo Olympics, his father, Dell Curry, told ESPN.Curry will be out for at least three months after surgery to repair a broken left hand he suffered in a game last week against the Phoenix Suns. While this season hasn’t gone according to plan for the Warriors, Curry had previously stated he intends to play in the Olympics, something he’s yet to do in his decorated career.“Absolutely. …
The science cops are on trial. Peer review, the process that many are led to believe enforces objectivity and validity in scientific papers, has come under fire lately (see 03/17/2006, 02/05/2006, 01/31/2006, 01/09/2006). In response to scandals and criticisms that the peer review as practiced is no guarantee against fraud, Nature is stepping out into uncharted waters. In an Editorial entitled “Peer review on trial,”1 Nature announced two initiatives that seem revolutionary if they become the new standard. One is to attach blogs to every item posted on News @ Nature, such as this one on the fish-o-pod, Tiktaalik. On a blog, readers can vociferate for or against a claim, rather than take the author’s word for it in a published paper that is assumed factual since it passed peer review. Another change opens the door to the hitherto secretive process of reviewing papers. The trial run of the new process is accompanied by an online debate on peer review at Nature.During the trial, which will last several months, Nature’s traditional approach to peer review will continue: typically, we send selected submissions to two or three experts whose identities are kept confidential. We believe that this approach works well. Meanwhile, over the next few weeks, the web debate will explore other approaches, as well as the potential for online techniques to unpack the various functions of conventional journals, the ethics of peer review, and more Our online trial opens up a parallel track of peer review for submitted papers for authors willing to go down that route. The traditional process will still be applied to all submissions selected for peer review. But we will also offer to post the submitted manuscript onto an open website. Anyone can then respond to it by posting online comments, provided they are willing to sign them.After a period of time, the website will close, and the author(s) will have the opportunity to modify the paper; Nature will also consider the comments posted before publishing it in the journal. The editors realize this opens research up to critique by journalists and the public as well. Nature is calling this a trial, not an experiment; they only want explore, expand, and test these ideas to see if they take hold. But, they end, “our core goal remains as always: to bring our readers the most stimulating content that our editorial skills can deliver.”1Editorial, “Peer review on trial,” Nature 441, 668 (8 June 2006) | doi:10.1038/441668a; Published online 7 June 2006.Notice they said stimulating content, not reliable content. Science fiction is stimulating, too, and so is alcohol. It’s about time peer review got some review itself, and lost some of its mystique. It’s a relatively recent tradition that many great scientific discoveries got by without just fine (e.g., Newton’s Principia). While scrutiny by others is wise for any claim (even in theology, the Apostle Paul said that “the spirits of the prophets are subject to the prophets”), peer review as practiced in science has created new problems while trying to solve others. In the information age, there are newer and better ways to screen out fraud and guarantee validity than to publish papers in high-profile journals that people are expected to trust simply because they have been peer reviewed. (Science reporters, among the worst of the believers, have tended to treat each issue as a message from the gods.) We want to see the day when Darwinian storytelling is no longer immune from scrutiny in the public arena, when scientists will be praised for the quality of their observations rather than their imaginations, and when claims outside the bounds of evidence are shamed out of science. Public review will not solve everything. Scientists risk their life work being stolen by rivals. But an author knowing his or her ideas will be exposed to knowledgeable critics willing to tie their names to their criticisms may be forced to act more reserved in their conclusions. That can be a good thing. No initiative or process is a substitute, however, for old fashioned honesty, an absolute requirement for credibility in any line of research.(Visited 11 times, 1 visits today)FacebookTwitterPinterestSave分享0
Johannesburg, 27 November 2013 – Brand South Africa will host a series of engagements with key stakeholders in the United Arab Emirates (UAE) from 4-5 December 2013 aimed at profiling South Africa’s value proposition for the UAE in particular and the Gulf region in general.These engagements are in line with Brand South Africa’s proactive promotion of South Africa as a globally competitive business destination.As such the South African delegation, which will be led by Minister Collins Chabane, will interact with Emirati business representatives, representatives of multinationals operating in the UAE and global South Africans based in the country.Brand South Africa will leverage of these engagements to highlight South Africa value proposition as a business destination to UAE businesses. This proposition will focus on South Africa as an investment destination on the one hand, and as a reliable partner in supporting the UAE’s developmental aspirations.South Africans have contributed to the development of the United Arab Emirates in, amongst others, the construction, health and financial industries. The Burj Al Arab which has become an iconic landmark in the country was constructed by Murray & Roberts a major South Africa construction company.Bilateral Economic Relations between South Africa and the UAEThe total bilateral trade between South Africa and the UAE is valued at approximately $3 billion (Dh11 billion)The UAE is the 24th largest investor in South Africa and is its largest trading partner in the Gulf Co-operation Council region. The UAE is also the 21st largest export market to South Africa.There is a growing community of South African nationals in the UAE, stimulated, in part, by a growing demand for South African skills. The major areas for employment of South Africans in the UAE include construction, hospitality, financial, medical, retail management and education.South African restaurant groups are also expanding into the UAE market: Nando’s, Butcher Shop, Meat & Co, Mug & Bean and Debonairs PizzaTrade and Investment Highlights:More than 135 South African companies have a presence in the UAE.Trade between the UAE and South Africa jumped 21.7% exceeding $1 billion in (2010).The volume of non-oil exports from Dubai to South Africa has jumped from Dh1.26 billion in 2009 to Dh2.41 billion in 2010, according to the Dubai Chamber of Commerce and Industry.Dubai imports from South Africa show growth from Dh3.011 billion to Dh3.055 billion in 2010.According to the Dubai Chamber mineral fuels, mineral oils, bituminous substances and mineral water are the top exports accounting for 48.1% of trade volumes.Other major Dubai export/ re-export products to South Africa include electrical machinery, equipment and parts consisting of 18% of the country’s foreign trade in 2010.South Africa’s Business Value Proposition to the UAE & the WorldWednesday 4 December 2013Roundtable on Infrastructure09h30RegistrationAll10h00OpeningMr Miller MatolaCEOBrand South Africa10h15Welcome addressAmbassador LekgoroSouth African Ambassador to the UAE10h25Introduction of Minister Collins ChabaneMs Chichi MaponyaChairpersonBrand South Africa10h30South Africa’s developmental indicators as a driver of competitivenessMinister Collins ChabaneDepartment of Performance Monitoring and EvaluationThe Presidency11h00Enhancing South Africa’s competitiveness through improving efficiencies in rail operationsMr Siyabonga GamaCEOTransnet Rail11h30Kwa-Zulu Natal Investment PropositionMr Neville MatjieGeneral Manager: CEO’s OfficeTrade and Investment, KZN12h00Interaction13h00Lunch and networkingMedia networkingHolding room14h00ClosureThursday 5 December 201309h00-16h00Networking platform with Global South African’sAmbassador Lekgoro About Brand South AfricaBrand South Africa is the official marketing agency of South Africa, with a mandate to build the country’s brand reputation, in order to improve its global competitiveness abroad. Its aim is also to build pride and patriotism among South Africans, in order to contribute to social cohesion and nation brand ambassadorship.Further resources from Brand South AfricaMedia are invited to visit http://www.southafrica.info/ for further resources which can be reproduced without any copyright infringement. Kindly attribute to Brand South Africa. Follow Brand South [email protected]_SA (https://twitter.com/Brand_SA)Tell us how you Play Your Parthttp://www.playyourpart.co.za/[email protected]#DoBestFor more information or to set up interviews, please contact:Arahna SinghBrand South Africa CommunicationsTel: +27 11 712 5061 Mobile: +27 (0) 82 491 2332Email: [email protected]: www.brandsouthafrica.comEnds